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Similar content being viewed by others Introduction Functional Connectivity (FC) has been proposed 1,2,3 as an approach to describe how brain regions coordinate to support higher cognitive functions

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53 Generally, the reported K m of PARP1 and CD38 for NAD + are lower than those of the sirtuins, suggesting that elevated activation of PARP1 or CD38 may limit endogenous SIRT activation by reducing NAD + content