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Reductive carboxylation supports redox homeostasis during anchorage-independent growth

This effect was observed by Yang et al

Tmea Mai for critical reading and linguistic corrections of the manuscript

314 Additionally, IDO1 inhibitors, such as epacadostat, target metabolic immunosuppression by blocking the conversion of tryptophan to kynurenine, a pathway that suppresses effector T cell activity while promoting regulatory T cell expansion