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Bhandage et al., Interestingly, subunits such as the and 2 subtypes which are less frequently studied were not only confirmed on transcript level in the human brain but were also demonstrated to undergo regulation (Bhandage et al., In the context of aging, evidence shows that the GABAergic system might be affected in older age, unable to exert its fine-tuned inhibitory efficacy on the neural circuits of the brain, ultimately affecting plasticity and adaptiveness to brain injury

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