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The restricted use of mucoadhesive particle systems in the clinic teaches us an important lesson for future inhaled drug development: preclinical and clinical studies should include various cell lines, tissues and disease models that represent the complexity of human lung biology (Fig

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So the problem here is that DVY's formula essentially chooses to maintain exposure to companies that have the potential to be 'value traps'

FASEB J 7:14421449 Beinert H, Holm RH, Munck E (1997) Iron-sulfur clusters: natures modular, multipurpose structures

Importantly, the lower level of HP [1- 13 C]glycine production in healthy rats precludes the possibility that the HP [1- 13 C]glycine detected in tumor animals was exclusively produced in the kidney 16 and then delivered to the brain