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Method Angiogenesis plays a major role in the process of neovascularization, so angiogenesis is a potential target for wound healing as the newer blood vessels formed over the injured surface are important to provide nutrients, immune cells, and oxygen for the healing of wounds

Hypothermic patients often require volume resuscitation during rewarming, as decreased ADH production can result in a cold-related diuresis and vasodilation naturally accompanies rewarming

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