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Integrating negative GFAP testing (i.e., below cut-off) to the clinical scores increased the PPV for LVO detection among all LVO scores: RACE with GFAP cut-off77pg/mL (56.5% to 76.4%), FAST-ED with GFAP68pg/mL (52.6% to 68.5%), 3i-SS with GFAP89pg/mL (52.9% to 71.4%)

Their use is based on global research and clinical experience as part of a comprehensive protocol

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Ethics approval and consent to participate As this is a review article based on previously published studies, no ethical approval or informed consent was required

The prohibited substances list includes peptide hormones