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One article proposed that excessive serotonin levels could explain classic symptoms of ME/CFS (433), as it would promote the release of excess CRH, and therefore cause chronic reactivation of the HPA axis (434)

conversely, compounds where the main structural units are coupled in any other manner are grouped as neolignans

For drug resistance regulation, metabolic reprogramming mediated by SSP activation represents a common mechanism underlying chemoresistance and targeted therapy resistance across pan-cancer