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Farkas A.J., Gilpin E.A., White M.M

Smoking is associated with the development of symptoms in a dose-dependent way and eosinophilia and airway hyperresponsiveness (AHR) increase the risk of developing dyspnea

This is thought to be due to cardiac -adrenergic stimulation as physiological response to increased myocardial work and oxygen demand [188]

However, there was no significant difference in sociodemographic characteristics, smoking-related characteristics, and the use of NRTs or prescription medications among characteristics related to smoking cessation interventions between the group who resumed smoking within 6 months (the relapser group) and the group who had been continuously abstinent from smoking throughout 6 months (the abstainer group)