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Importantly, C3G exhibited metal-coordination bonds with the binuclear copper active site via oxygen atoms of the ( m )meta-diphenols (A-ring) while EC and CH exhibited similar interactions with the mh-Tyr via oxygen atom on the ( o )ortho-diphenols or catechol group (B-ring) (Table S1, Fig

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TRT is typically recommended for men who have been diagnosed with low testosterone levels and are experiencing symptoms such as fatigue, decreased libido, muscle loss, or cognitive difficulties

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European Journal of Pharmacology, 2006

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militaris effectively regulated key proteins such as HO-1, Nrf2, Kelch-like ECH-associated protein-1 (Keap1), and quinone oxidoreductase 1 (NQO1) in the Nrf2 signaling pathway [131]

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