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Isola et al., 2024b

While compounded semaglutide and tirzepatide match KLOWs 20C pre-reconstitution and 28C post-reconstitution requirements, branded pens like Wegovy include excipients that extend refrigerated shelf life to 56 days vs KLOWs 28-day window

Over 16 weeks, SHRs fed an oat protein diet exhibited significant reductions in both systolic and diastolic blood pressure, along with improvements in cardiac function and oxidative stress markers, notably increased NO levels and decreased TNF- levels

Side Effects Common Headache Nausea, vomiting Abdominal pain Constipation or diarrhea Bloating / flatulence Long-Term or Serious Vitamin B12 deficiency Hypomagnesemia Increased risk of fractures (hip, spine, wrist) Kidney injury (interstitial nephritis) C

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