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Hypothyroidism is a common culprit, as low thyroid hormone levels slow down metabolism and gut function

Older adults are more likely to be on multiple medications, increasing the potential for interactions

Together, all these findings emphasize the essential role of choline availability in macrophage preparedness for an efficient immune response to diverse triggers and reveal that the impact of impaired choline metabolism and utilization on inflammatory molecular pathways is cell- and stimulus-specific

By repairing gut mucosa, dampening systemic cytokine release, and modulating immune pathways, they help stabilize the gutbrain axisa key regulator of nocturnal comfort and sleep continuity

[link] Rabinowitz, J