Vol. XVIII · Free shipping $75+ · Read the collection
Feature · Product Review
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SAGE Publications Inc

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doi: 10.1038/s41422-019-0263-3 39 YadavPSharmaPSundaramSVenkatramanGBeraAKKarunagaranD

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10.1155/2019/2654910 56 YuJ.MaZ.ShettyS.MaM.FuJ

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This recent preclinical study showed that the metabolism of racemic ketamine to (2 R ,6 R )-HNK is necessary for the antidepressant effects of ketamine, and that this metabolite itself shows antidepressant-like effects in mice that seem to be independent of the NMDAR

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