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Neuropsychobiology 80:502515

Cellular GSSG accumulation is limited by the fact that cells employ multiple redundant reductive pathways to reduce cytosolic GSSG or to actively export GSSG to the extracellular environment, for example by MRP1 in mammalian cells or to alternative subcellular compartments, for example by Ycf1 in yeast [21, 59]

There was a statistically significant (p-values 12 months, 17% (n=219)

In 12 newly diagnosed LN patients, synbiotic administration induced significant alterations in gut microbiota composition: the relative abundance of pathogenic bacteria (including Prevotella, Bacteroides , and unclassified Enterobacteriaceae ) decreased, whereas beneficial bacterial populations (such as Actinobacteria and Firmicutes ) showed marked increases [95]

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