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Bismuth also increased the levels of actin filament and vesicle tethering complex, suggesting enhanced vesicle exocytosis, while in GSH-depleted cells, bismuth greatly induces metallothionein expression, ubiquitin-mediated proteolysis, and DNA mismatch

They are added to form a stack and explore their combined influence on organisms during clinical studies

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However, this restriction might be removed, and interest in SODs medicinal qualities increased with advancements in its formulation

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