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In comparison to normal cells, cancer cells are characterized by an increased H 2 O 2 production rate and an impaired redox balance thereby affecting the microenvironment as well as the anti-tumoral immune response

In addition, according to Herbert et al

Various topical formulations of vitamin C with concentration range of 3.75%30% have been considered in melasma, however, in most studies, vitamin C concentration was less than 10% for the purpose of skin photodamage and melasma treatment ( 5.1.11 Glycolic acid Glycolic acid, as an -hydroxy acid (AHA), have a crucial rule in cell-adhesion disruption and further skin desquamation

Solid dispersions represent advanced fourth-generation systems that incorporate both solubility enhancement and controlled release properties