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After 12 weeks of twice-daily application over the entire face, evaluation by visiometry revealed a significant reduction in two skin-roughness parameters (R2 and R3) among the women in the L-carnitine group, reflecting a visible improvement in skin texture and a decrease in wrinkles compared with the placebo

Malfatti CR, Royes LF, Francescato L, Sanabria ER, Rubin MA, Cavalheiro EA, Mello CF (2003) Intrastriatal methylmalonic acid administration induces convulsions and TBARS production, and alters Na+, K+ -ATPase activity in the rat striatum and cerebral cortex

These proteins are located on the IMM and interact with the optic atrophy protein 1 (Opa1)

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Rats were housed under with ad libitum source of food and water throughout the experiment