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Building upon our extensive proteomics data sets, our initial analysis sought to filter kinases that were repeatedly detected in complex with and/or in proximity to NHR-49

This study marked the first biochemical evidence suggesting that H 2 O 2 produced by colonic epithelial cells is the previously unidentified chemical secreted by colonic epithelial cells leading to the development of UC

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Spinosa M, Su G, Salmon MD, Lu G, Cullen JM, Fashandi AZ, et al