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1 Background Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder affecting 420% of women of reproductive age worldwide, depending on diagnostic criteria ( 2 Methods 2.1 Search strategy and databases A structured literature search was conducted across PubMed and Google Scholar to identify studies examining the therapeutic role of apigenin and ellagic acid in polycystic ovarian syndrome (PCOS)