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Melanosis Coli Case Studies: Understanding the Differential Diagnosis Leopard skin appearance on colonoscopy. Melanosis coli is a condition characterized by dark brown or black pigmentation of the colon lining, often resulting from the prolonged use of anthraquinone laxatives like senna Pigmentation characteristics of melanosis coli. (A) Representative Download Scientific Diagram Understanding Melanosis Coli and Constipation Causes Melanosis coli: a case report The Egyptian Journal of Internal Medicine Springer Nature Link
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