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The inadequate adoption of preventive measures and suboptimal management of risk factors associated with atherosclerotic cardiovascular disease (ASCVD) significantly contribute to this burden among adults ( CVD risk estimates among newly diagnosed patients with hypertension, diabetes, or dyslipidemia could be improved by dynamic changing smoking habits, as well as by an objective and time-updated assessment of other CVD risk factors

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Current research suggests that while PG and VG are significantly less harmful than the tar and carbon monoxide found in combustible cigarettes, they are not biologically inert when inhaled