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But truth be told, most of the time, Why? is not helpful

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This pattern suggests sophisticated regulatory control rather than simple up- or down-regulation

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Nyangwa et al., 2022), led to the introduction of 69 months regimens of bedaquiline, pretomanid, linezolid, with or without moxifloxacin (BPaL-M or BPaL, respectively), offering improved outcomes compared to older treatment strategies (Johnson et al., 2024)