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Patients with uncontrolled T1D have high GH, low total and free IGF-I levels ( Table 1

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10.1038/ki.2013.209 Summary Keywords chronic kidney disease, disulfiram, network pharmacology, molecular dynamics, renal fibrosis Citation Patil VS, Patil CR, Patel HM and Kumar A (2025) Exploring disulfiram mechanisms in renal fibrosis: insights from biological data and computational approaches

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Evidence linking apoE with autophagy was provided by experiments using apoE-expressing astrocytes, which revealed a decreased autophagic flux in apoE4-expressing astrocytes as compared to apoE3 [66]