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In the STI + CoQ10 group, CoQ10 had a greater effect on the myelinated axon area and myelin sheath thickness than in the LTI + CoQ10 group

A: Purity is critical

As the metabolic hub of the cell 7 , the mitochondrion undergoes extensive remodeling during activation to support anabolism, including increased biomass, morphological changes, augmented reactive oxygen species (ROS) production, and altered metabolic pathways within minutes of T cell receptor (TCR) ligation 8,9

However, as research progresses, disturbances in cellular and mitochondrial metabolism have been recognized as significant contributors to the development of epilepsy

10.1038/s41580-024-00727-x 78 WeyemiU.Lagente-ChevallierO.BoufraqechM.PrenoisF.CourtinF.CaillouB.et al (2012)