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Throughout the discovery of agents targeting glutaminolysis, none have yet been used clinically 197

Measurement of polyamine metabolism substances contents and enzymes activities Endogenous polyamine content: 0.3 g fresh leaf sample was ground into a homogenate in pre-cooled perchloric acid (PCA, 4 ml, 5% V/V) and then kept at 4C for 1 h

One-Carbon Metabolism (OCM) is a series of core biochemical networks in organisms that revolve around the transfer and utilization of single carbon units (e.g., methyl, formyl, methylene)

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In addition, administration of the antioxidant GSH can fully prevent all of the LOsG-induced detrimental events