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Since GSH, cysteine, and ascorbic acid had comparable radical scavenging activities to the gsh2 mutant supernatant (Extended Data Fig

Mechanism of Action Comparison# Carnosine# Carnosine (beta-alanyl-L-histidine) is an endogenous dipeptide found at high concentrations in skeletal muscle (20-30 mM), cardiac muscle, and brain tissue

To test this hypothesis, we assessed the interaction of OLFM4 with FAT1

It has already been shown that GSH levels are reduced in the cerebrospinal fluid (CSF) of MS patients and that GPX4 activity is affected during MS pathology [18]

The results of the LFQ proteomics of the patient data are reported in Supplementary Data 2