These new drugs work in different ways than drugs in the other classesthat is, they have novel mechanisms of action
Outcome among patients with acute renal failure needing continuous renal replacement therapy: a single center study
This injection is essentially 0.9% sodium chloride (NaCl) dissolved in sterile waterwith 9 mg of sodium chloride per milliliter, making it isotonic with blood and tissues. The isotonic nature means it has the same salt concentration as normal body fluids, so it wont cause cells to shrink or swell when injected. In addition to salt,each milliliter contains about 9 mg of benzyl alcohol (0.9%) as the bacteriostatic agent. The benzyl alcohol does not treat infection, but its job is to keep the solution sterile by inhibiting bacterial growth if the vial is used more than once. The solution is labeled nonpyrogenic, meaning its free from substances that cause fever, and its intended for parenteral use (injection). Because its a USP-grade preparation, it meets quality standards for purity and sterility required for injectable solutions
In patients with controlled plasma phosphate, this can be achieved by giving either calcitriol or one of its synthetic analogs, or by administering oral calcium supplements
By providing both, you ensure the warehouse is stocked for immediate needs while the assembly line continues to produce more for the future
