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The appeal of cigar and cigarillos alongside conventional cigarettes in duty free flavor portfolios is also notable, as travelers increasingly seek to diversify their tobacco purchases across product types within a single duty free visit

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Chronic exposure to this smoke causes metaplastic alterations to the respiratory mucosa with an increase in the number and size of goblet cells and consequent increase in upper airway secretion.17,18 Cohen et al.13 and Kreindler et al.19 also showed in vitro that exposure to cigarette smoke inhibits chloride transport in epithelial cells, causing physiological alterations similar to those found in patients with cystic fibrosis