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In arsenic trioxide (1 M) and ATRA (1 M) synergistically play inhibitive effect on OCI-AML3 and primary AML cells harboring an NPM1 mutation, with little effect on non-APL wild type NPM1 AML cells

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Rats fed with low-protein diets (which are particularly poor in sulfurated amino acids) will exhibit increased hepatic G-SH and GGT activity, with both returning to baseline values when methionine is added to the low-sulfur diet [19]