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The patients showed a pronounced deficit in total serum Se and SELENOP concentrations when compared to reference data from a cross-sectional analysis of the European EPIC study (Reference Moghaddam, Heller and Sun40)

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In vitro experiments performed in a previously published study (140) have confirmed the occurrence of ferroptosis without autophagy or apoptosis

A total of eight studies were identified reporting 1-AGP levels in CD patients based on our research criteria [119, 120, 135, 142, 148,149,150,151]

In a centrifuge tube layer 2 volumes of heparinized blood over 1 volume of the density barrier (see Figure 1 and Section 2c)

Additionally, future studies should investigate the long-term effects of microbiome-based interventions and explore the potential of personalized medicine approaches tailored to individual patients gut microbial profiles (Cunningham et al., 2021)