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Selvarajah, D., Wilkinson, I

Results of phase III studies of daratumumab in combination with bortezomib-thalidomide-dexamethasone, bortezomib-melphalan-prednisone, or lenalidomide-dexamethasone and of isatuximab in combination with bortezomib-lenalidomide-dexamethasone have shown significant benefit from treatment with anti-CD38 combinations in transplant-eligible or -ineligible NDMM patients, compared with standard treatment [13, 14, 86]

Methylation is a common regulation process of gene expression that influences cellular development and function 22 , which is dependent on SAM as a methyl donor

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**Product contains benzyl alcohol as an inactive ingredient Contraindications for Benzyl Alcohol This preparation is not advised in patients who are sensitive to cobalt and/or vitamin B12