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Higher levels of NLRP3 inflammasomes have been reported in the peripheral blood mononuclear cells and granulosa cells of women with PCOS than in the control group [119, 121]

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Induction of ER stress and subsequent autophagy is another common cellular response, marked by increased expression of UPR components and autophagy markers such as LC3B

Gastrointestinal Effects: Mild nausea, abdominal cramping, bloating, and flatulence may occur, especially during the initial supplementation period

Our results showed that I/R causes 16-fold increases in ALT and AST, and a 1.6-fold increase in ALP activity (Table 5), following the literature data showing that I/R causes a much greater increase in serum ALT and AST activity than in ALP 66