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The ERO1-PDI axis is thought to be the main pathway for disulfide bond formation in ER (Wang et al., 2014)

Plasma glutathione levels decreased with cognitive decline among people with mild cognitive impairment (MCI): a two-year prospective study

When it is compromised, skin becomes more vulnerable to bacteria, pollution, allergens, and UV damage

Acknowledgements The study is supported by a Singapore EDB-IPP grant (grant number: RL2012035)

In T2D patients (n = 25, age 2565), consumption of 1 g L-citrulline twice a day for 4 weeks reduces the T2D-induced increase in arginase activity and increases plasma nitrites, effects corroborated by improvement of ACh-induced relaxation in ex vivo mouse aortic rings incubated (24-h) in low or high glucose-containing media and increases in NO production in ECs treated with high glucose (Shatanawi et al., 2020)