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For researchers dealing with autoimmune conditions or chronic inflammatory states, this modulation rather than suppression mechanism is particularly relevant

Rev Endocr Metab Disord 25(1):215237

ICARIA-MM and APOLLO In preclinical studies, pomalidomide was found to augment the direct apoptotic and immunomodulatory activities of isatuximab [29, 31]

Therefore, inflammatory conditions may increase GGT synthesis, potentially acting as a cellular protective mechanism under increased oxidative stress or promoting inflammatory progression