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Nutrients 13 , 2498 (2021)

5.4 Gene modulation therapy DNA damage induced by excessive ROS induces inappropriate transcriptional activation, resulting in the inability of stem cells to perform a range of essential physiological activities and greatly reducing the efficiency of osteogenic differentiation

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

NaBPC157 was applied as a prophylactic co-treatment or therapeutic salutary regimen (10 g or 10 ng/kg i.p.)