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The concentration of carbon monoxide emitted from cigarettes is higher than what is emitted from vehicle exhaust. Smoke from e-cigarettes and vaporizers is considered secondhand smoke as well, but research is underway to determine just how harmful these newer products are to health

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Cigarette smoke contains substances such as polycyclic aromatic hydrocarbons that induce liver enzymes, particularly cytochrome P450 1A2 (CYP1A2)