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NNMT has been linked to a number of chronic diseases/conditions

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Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR: Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp 70 S6 kinase, DNA synthesis, and glucose transporter translocation

On darker skin, the risk of post-inflammatory hyperpigmentation (PIH) is real, and the last thing we want is to trade one discoloration problem for another