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Description

Tumor-derived myeloid-derived suppressor cells (MDSCs) are critical tumor immunosuppression components

Herein, we have approached this by analyzing transcriptomic and metabolomic responses elicited in colon cancer cells that persist after exposure either to the CDK4/6i Palbociclib or the glutaminase inhibitor Telaglenastat (CB-839), or their combination, in vitro and in vivo