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It is often accompanied by chronic fatigue, muscle loss, osteoporosis, depressive states or increased risk of cardiometabolic disorders

, 21 , 396-413, doi: Guo, J., Xu, B., Han, Q., Zhou, H., Xia, Y., Gong, C., Dai, X., Li, Z., and Wu, G

reported that hypoxia-treated MSCs mitigate renal tubular cell apoptosis and preserve renal function during rat I/R injury by promoting tissue autophagy