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2.3.1 The System Xc-GSH-GPX4 axis The heat shock protein 90 (HSP90) plays an important role in protein maturation, stabilisation, and activation (Wickramaratne et al., 2023)

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More than two-thirds of patients already present with advanced disease at the time of diagnosis [3]

performed transcriptomic profiling which demonstrated that Pterostilbene influenced the expression of genes related to sulfur metabolism by downregulating six genes (ECM17, MET3, MET14, MET16, MET10, and MET6) that encode enzyme regulating methionine biosynthesis (23)

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