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The discovery, published in 1992, landed the pharmacologist on the front page of The New York Times as well as on Popular Mechanics ' list of the greatest scientific discoveries of the 20th century

Emerging pathways of interest: Novel interactions identified in the PPI network suggest additional pathways requiring further investigation including ion transport regulation by genes like RHBG , which may influence tissue homeostasis

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These mutations were linked to either increased or decreased risk of developing specific cancers, including prostate, colorectal, thyroid, lung, melanoma, and breast cancers (91)Ivarsdottir EV, et al

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