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Importantly, the enzymatic activity of TETs is regulated by 2-oxoglutarate (2OG) as a cofactor and suppressed by metabolites such as 2-hydroxyglutarate (2HG) as a competitor of 2OG

According to Box Office Mojo, a box office revenue tracking website, films in which Schwarzenegger has acted have grossed a total of more than $1.7 billion within the United States, with an average of $67 million per film and total $4.0 billion worldwide

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