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In response to growing criticism of the cost of their drugs, Novo Nordisk, the company that manufactures Ozempic and Wegovy, reported last year that rebates and other fees (across all payers) accounted for about 40% of the cost of the two drugs and that they expected rebates to grow

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To produce these class-switched, affinity-matured immunoglobulins in serum or mucosal fluids, GC B cells must leave the GC as antibody-secreting, short-lived plasmablasts (PBs) or long-lived PCs [51]

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