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This recent rapid increase in demand (Watanabe et al., 2023), spurred in part by celebrity endorsements touting the cosmetic benefits of these drugs (Klein, 2023), led to an FDA-designated supply shortage of liraglutide, semaglutide, and tirzepatide

In skincare circles, they are often marketed as advanced signaling molecules capable of stimulating collagen, improving elasticity, and reversing visible aging