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Given the importance of these metabolites in mediating chronic intestinal inflammation, additional well-designed and sufficiently powered clinical trials in dogs with CIE are warranted

The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

High ROS levels are linked to diseases like Alzheimers, cardiovascular disease, and cancer

In parallel, previous studies have found that dexamethasone can increase parathyroid hormone synthesis, which may be an important pathogenic role in persisting hyperparathyroidism [164, 165]

Improvement measures: Neutralizing agents can be combined to eliminate the interference of antibacterial components, or membrane filtration can be adopted to enhance sensitivity