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Centers for Disease Control and Preventions website on the different kinds of immunizations and what to know before getting them

Because the injections are given infrequently with a very small needle (typically a 25-gauge needle is adequate), this is not usually a very unpleasant experience for the cat

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B12 injections tend to be most useful for: Patients on GLP-1 medications (semaglutide, tirzepatide) who feel fatigue in early weeks Patients with low energy, brain fog, or mood symptoms Vegetarians or vegans (plant foods don't contain B12) Adults over 50 (B12 absorption drops with age) Patients who've had digestive surgeries (bariatric, gallbladder) that affect absorption They're generally safe B12 is water-soluble, so your body excretes what it doesn't use