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In contrast, hemolysis occurring with the G6PD Mediterranean variant is more severe because a larger population of circulating erythrocytes is vulnerable to injury

In the central nervous system, iron mainly enters the brain through the blood-brain barrier and the blood-cerebrospinal fluid barrier

Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Wu et al., 2022

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