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This dual role, stimulating both synthesis and controlled degradation, is characteristic of wound healing rather than simple collagen accumulation

Facial skin often shows visible changes during rapid weight loss, sometimes called Ozempic face in popular media

Moreover, MDM2 inhibitors like Nutlin-3 and its derivatives (Idasanutlin/RG7388) have commenced clinical studies for solid tumors and hematological malignancies

doi: 10.1007/s00011-010-0304-3 217 SerekP.Oleksy-WawrzyniakM

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