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Even though total body weights were similar on a normal chow diet, total WAT mass was reduced in HSL null mice compared to control and this difference was exaggerated on a high fat diet, with total WAT weight more than 70% lower in HSL null mice than in control

The reason behind this is that they can enhance metabolic function, encourage fat export from the liver, and provide nutritional support

PMID: 30473097

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B12 deficiency can also lead to the destruction of immature red blood cells in the bone marrow, which can cause jaundice (yellowing of the skin and whites of the eyes)