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Although the steric hindrance of amino is small, the bond length of Cu 2+ /amino coordination is longer than that of Cu 2+ /imidazolyl coordination, resulting in the worse stability of Structure B

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Dissecting the mechanisms of immune checkpoint therapy

It is well established that exhaustive exercise increases circulating NH 3 (Reference Weiner and Verlander68) , and one possible explanation for the enhanced glutamine within the brain could be to detoxify the brain via the removal of NH 3 through the synthesis of glutamine using GS (Reference Conway and Hutson69)

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