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The CySSO 2 H (perthiosulfinic) and CySSO 3 H (perthiosulfonic) oxidation products of persulfides can be recycled back by the reduction of their SS moieties, which does not occur in the case of the CySO 3 H oxidation product of unmodified (unsulfhydrated) cysteine residues on proteins [7]

As mentioned above, there are more than 100 Akt substrates mainly including GLUT4, FOXO1, GSK3, mTORC1, SREBP-1c, TSC1/2, PRAS40, ABHD15, PDE3B

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